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Article

Genetic diversity of the KIR/HLA system and outcome of patients with metastatic colorectal cancer treated with chemotherapy.

PloS one - 1 Jan 2014

De Re Valli, Caggiari Laura, De Zorzi Mariangela, Talamini Renato, Racanelli Vito, D' Andrea Mario, Buonadonna Angela, Zagonel Vittorina, Cecchin Erika, Innocenti Federico, Toffoli Giuseppe

Abstract excerpt

OBJECTIVE: To explore genes of the killer-cell immunoglobulin-like receptor (KIR) and of the HLA ligand and their relationship with the outcome of metastatic colorectal cancer (mCRC) patients treated with first-line 5-fluorouracil, leucovorin, and irinotecan (FOLFIRI). METHODS: A total of 224 mCRC patients were screened for KIR/HLA typing. The determination of the KIR/HLA combinations was based upon the gene...

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Identifiers

PMID: 24497922
DOI: 10.1371/journal.pone.0084940
PMCID: PMC3908861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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