Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Utility of large consanguineous family-based model for investigating the genetics of type 2 diabetes mellitus.

Gene - 10 Sept 2014

Al-Sinani Sawsan, Hassan Mohammed Othman, Zadjali Fahad, Al-Yahyaee Said, Albarwani Sulayma, Rizvi Syed, Jaju Deepali, Comuzzie Anthony, Voruganti Venkata Saroja, Bayoumi Riad

Abstract excerpt

OBJECTIVES: This study examined the utility of a family-based model for replicating the results of genome-wide association studies (GWAS) of type 2 diabetes (T2D). METHODS AND RESULTS: In a total of 232 members of a large consanguineous Omani Arab pedigree (age: 16-80years), there were 27 diabetics and 50 prediabetics (17 with impaired fasting glucose and 33 with impaired glucose tolerance). All 232 individuals...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arabs
Share to Consanguinity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Genome-Wide Association Study

Share to Glucose Intolerance

Share to Lod Score

Share to Models, Genetic

Share to Prediabetic State

Source

Identifiers

PMID: 24993573
DOI: 10.1016/j.gene.2014.06.053

Genes

CAPN10
FTO
KCNJ11
MGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Utility of large consanguineous family-based model for investigating the genetics of type 2 diabetes mellitus.PMID 24993573Read ↗

A genome-wide search for type 2 diabetes susceptibility genes in an extended Arab family.Semantic proximity Read ↗

Association of gene variants with susceptibility to type 2 diabetes among OmanisSemantic proximity Read ↗

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.Semantic proximity Read ↗

Recessive Genome-Wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes.Semantic proximity Read ↗

Investigating the potential effect of consanguinity on type 2 diabetes susceptibility in a Saudi population.Semantic proximity Read ↗

A family study in Oman: large, consanguineous, polygamous Omani Arab pedigrees.Semantic proximity Read ↗

A generalized family-based association test for dichotomous traits.Semantic proximity Read ↗

Replication of Type 2 diabetes-associated variants in a Saudi Arabian population.Semantic proximity Read ↗

Type 2 Diabetes Risk Prediction Incorporating Family History Revealing a Substantial Fraction of Missing HeritabilitySemantic proximity Read ↗

Combining genetic markers and clinical risk factors improves the risk assessment of impaired glucose metabolism.Semantic proximity Read ↗

Validation of type 2 diabetes risk variants identified by genome-wide association studies in Han Chinese population: a replication study and meta-analysis.Semantic proximity Read ↗

Evaluation of genome-wide association study-identified type 2 diabetes loci in African Americans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.