Article
Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Jun 2006
Yamamoto Tae, Kyo Motoki, Kamiya Terue, Tanaka Toshiyuki, Engel James Douglas, Motohashi Hozumi, Yamamoto Masayuki
Abstract excerpt
Small Maf transcription factors possess a basic region-leucine zipper motif through which they form homodimers or heterodimers with CNC and Bach proteins. Different combinations of small Maf and CNC/Bach protein dimers bind to cis-acting DNA elements, collectively referred to as Maf-recognition elements (MAREs), to either activate or repress transcription. As MAREs defined by function are often divergent from the...
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