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Article

Smoking behaviour modifies IL23r-associated disease risk in patients with Crohn's disease.

Journal of gastroenterology and hepatology - 1 Feb 2015

Doecke James D, Simms Lisa A, Zhao Zhen Zhen, Roberts Rebecca L, Fowler Elizabeth V, Croft Anthony, Lin Angela, Huang Ning, Whiteman David C, Florin Timothy H J, Barclay Murray L, Merriman Tony R, Gearry Richard B, Montgomery Grant W, Radford-Smith Graham L

Abstract excerpt

BACKGROUND AND AIM: The etiology of Crohn's disease (CD) implicates both genetic and environmental factors. Smoking behavior is one environmental risk factor to play a role in the development of CD. The study aimed to assess the contribution of the interleukin 23 receptor (IL23R) in determining disease susceptibility in two independent cohorts of CD, and to investigate the interactions between IL23R variants,...

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Source

Identifiers

PMID: 24989722
DOI: 10.1111/jgh.12674

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Smoking behaviour modifies IL23r-associated disease risk in patients with Crohn's disease.PMID 24989722Read ↗

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