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Article

Differences in genetic background between active smokers, passive smokers, and non-smokers with Crohn's disease.

The American journal of gastroenterology - 1 May 2010

van der Heide Frans, Nolte Ilja M, Kleibeuker Jan H, Wijmenga Cisca, Dijkstra Gerard, Weersma Rinse K

Abstract excerpt

OBJECTIVES: Smoking behavior and genetic variations are important factors for the development of Crohn's disease (CD), but studies investigating the interaction between smoking and genetic background are scarce. We studied allelic associations of 19 confirmed variants located in 14 CD-associated genes or loci, in CD patients stratified for active smoking at diagnosis and passive smoking in childhood. METHODS:...

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Source

Identifiers

PMID: 19953089
DOI: 10.1038/ajg.2009.659

Genes

PTPN2
NOD2
CCNY
DLG5
IRGM

Variants

rs17234657

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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