Article
IL-2 inhibited the generation of CD4+ memory T cells.
Cell biochemistry and biophysics - 1 Dec 2014
Lu Hongjuan, Chen Jie, Nie Xuefeng, Liu Cong, Sun Weimin
Abstract excerpt
The survival of T cells at different stages of development is dependent on extrinsic signals. IL-7 is necessary for the development of memory T cells. IL-7 could induce and maintain the differentiation, survival, and proliferation of CD4(+) memory T cells, and the roles of IL-2 and IL-15 in the generation of CD4(+) memory T cells were still unclear. A CD4(+) memory T cells in vitro generated system by adding...
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