Article
A compare-and-contrast NMR dynamics study of two related RRMs: U1A and SNF.
Biophysical journal - 1 Jul 2014
DeKoster Gregory T, Delaney Kimberly J, Hall Kathleen B
Abstract excerpt
The U1A/U2B″/SNF family of small nuclear ribonucleoproteins uses a phylogenetically conserved RNA recognition motif (RRM1) to bind RNA stemloops in U1 and/or U2 small nuclear RNA (snRNA). RRMs are characterized by their α/β sandwich topology, and these RRMs use their β-sheet as the RNA binding surface. Unique to this RRM family is the tyrosine-glutamine-phenylalanine (YQF) triad of solvent-exposed residues that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
