Article
Bird to human transmission biases and vaccine escape mutants in H5N1 infections.
PloS one - 1 Jan 2014
Wagh Kshitij, Bhatia Aatish, Greenbaum Benjamin D, Bhanot Gyan
Abstract excerpt
BACKGROUND: The avian influenza A H5N1 virus occasionally infects humans, with high mortality rates. Although all current human infections are from avian-to-human transmission, it has been shown that H5N1 can be evolved to transmit between mammals, and is therefore a pandemic threat. For H5N1 surveillance, it is of interest to identify the avian isolates most likely to infect humans. In this study, we develop a...
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