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Article

Scoring Amino Acid Mutations to Predict Avian-to-Human Transmission of Avian Influenza Viruses.

Molecules (Basel, Switzerland) - 29 Jun 2018

Qiang Xiaoli, Kou Zheng, Fang Gang, Wang Yanfeng

Abstract excerpt

Avian influenza virus (AIV) can directly cross species barriers and infect humans with high fatality. Using machine learning methods, the present paper scores the amino acid mutations and predicts interspecies transmission. Initially, 183 signature positions in 11 viral proteins were screened by the scores of five amino acid factors and their random forest rankings. The most important amino acid factor (Factor 3)...

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Identifiers

PMID: 29966263
DOI: 10.3390/molecules23071584
PMCID: PMC6100476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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