Article

Quantifying within-host diversity of H5N1 influenza viruses in humans and poultry in Cambodia

2019-06-27

Abstract excerpt

Avian influenza viruses (AIVs) periodically cross species barriers and infect humans. The likelihood that an AIV will evolve mammalian transmissibility depends on acquiring and selecting mutations during spillover, but data from natural infection is limited. We analyze deep sequencing data from infected humans and domestic ducks in Cambodia to examine how H5N1 viruses evolve during spillover. Overall, viral popula...

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Literature Corpus work: b9f8dd2c-245f-50f6-a329-9d4c1c2c5453
DOI: 10.1101/683151

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