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Article

Quantifying within-host diversity of H5N1 influenza viruses in humans and poultry in Cambodia.

PLoS pathogens - 1 Jan 2020

Moncla Louise H, Bedford Trevor, Dussart Philippe, Horm Srey Viseth, Rith Sareth, Buchy Philippe, Karlsson Erik A, Li Lifeng, Liu Yongmei, Zhu Huachen, Guan Yi, Friedrich Thomas C, Horwood Paul F

Abstract excerpt

Avian influenza viruses (AIVs) periodically cross species barriers and infect humans. The likelihood that an AIV will evolve mammalian transmissibility depends on acquiring and selecting mutations during spillover, but data from natural infection is limited. We analyze deep sequencing data from infected humans and domestic ducks in Cambodia to examine how H5N1 viruses evolve during spillover. Overall, viral...

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Identifiers

PMID: 31951644
DOI: 10.1371/journal.ppat.1008191
PMCID: PMC6992230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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