Article
Novel phylogenetic algorithm to monitor human tropism in Egyptian H5N1-HPAIV reveals evolution toward efficient human-to-human transmission.
PloS one - 1 Jan 2013
Perovic Vladimir R, Muller Claude P, Niman Henry L, Veljkovic Nevena, Dietrich Ursula, Tosic Dusan D, Glisic Sanja, Veljkovic Veljko
Abstract excerpt
Years of endemic infections with highly pathogenic avian influenza (HPAI) A subtype H5N1 virus in poultry and high numbers of infections in humans provide ample opportunity in Egypt for H5N1-HPAIV to develop pandemic potential. In an effort to better understand the viral determinants that facilitate human infections of the Egyptian H5N1-HPAIVvirus, we developed a new phylogenetic algorithm based on a new distance...
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