Article
Pupylated proteins in Corynebacterium glutamicum revealed by MudPIT analysis.
Proteomics - 1 Jun 2014
Küberl Andreas, Fränzel Benjamin, Eggeling Lothar, Polen Tino, Wolters Dirk Andreas, Bott Michael
Abstract excerpt
In a manner similar to ubiquitin, the prokaryotic ubiquitin-like protein (Pup) has been shown to target proteins for degradation via the proteasome in mycobacteria. However, not all actinobacteria possessing the Pup protein also contain a proteasome. In this study, we set out to study pupylation in the proteasome-lacking non-pathogenic model organism Corynebacterium glutamicum. A defined pup deletion mutant of C....
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