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Article

Expression of G protein-coupled estrogen receptor in irritable bowel syndrome and its clinical significance.

International journal of clinical and experimental pathology - 1 Jan 2014

Qin Bin, Dong Lei, Guo Xiaoyan, Jiang Jiong, He Yangxin, Wang Xiaoyan, Li Lu, Zhao Juhui

Abstract excerpt

OBJECTIVES: Estrogen is suggested to participate in pathogenesis of irritable bowel syndrome (IBS), but expression of G protein-coupled estrogen receptor (GPER) in the colon of IBS patients has never been investigated. The aim of this study was to investigate the expression of GPER and classical estrogen receptors in the colon of IBS patients and healthy controls. METHODS: Colonic biopsies were obtained by...

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PMID: 24966932
PMCID: PMC4069936

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