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The G-protein-coupled estrogen receptor, a gene co-expressed with ERα in breast tumors, is regulated by estrogen-ERα signalling in ERα positive breast cancer cells

2022-06-17

Abstract excerpt

<h4>Purpose</h4> The purpose of this study was to assess the relationship between GPER, a seven transmembrane G-protein coupled estrogen receptor, and ERα in breast tumors, and to make inroads into the mechanistic basis and clinical significance. <h4>Methods</h4> TCGA-BRCA data was mined to examine the relationship between GPER and ERα expression. GPER mRNA, and protein expression were analyzed in ERα-positive o...

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Literature Corpus work
6f88f849-e90e-54de-843f-2eaa8218e601
DOI
10.1101/2022.06.14.496079
Open publication

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The G-protein-coupled estrogen receptor, a gene co-expressed with ERα in breast tumors, is regulated by estrogen-ERα signalling in ERα positive breast cancer cellsDOI 10.1101/2022.06.14.496079
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