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Role of GPER-Mediated Signaling in Testicular Functions and Tumorigenesis

17 Sept 2020

Abstract excerpt

Estrogen signaling plays important roles in testicular functions and tumorigenesis. Fifteen years ago, it was discovered that a member of the G protein-coupled receptor family, GPR30, which binds also with high affinity to estradiol and is responsible, in part, for the rapid non-genomic actions of estrogens. GPR30, renamed as GPER, was detected in several tissues including germ cells (spermatogonia,...

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PMID: 32957524
DOI: 10.3390/cells9092115

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