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Article

Estrogen receptors in human bladder cells regulate innate cytokine responses to differentially modulate uropathogenic <i>E. coli</i> colonization

2020-05-30

Abstract excerpt

The bladder epithelial cells elicit robust innate immune responses against urinary tract infections (UTIs) for preventing the bacterial colonization. Physiological fluctuations in circulating estrogen levels in women increase the susceptibility to UTI pathogenesis, often resulting in adverse health outcomes. Dr adhesin bearing Escherichia coli (Dr E. coli ) cause recurrent UTIs in menopausal women and acute pyel...

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Literature Corpus work
e26dcbd3-9e7a-5182-bfeb-03c9e4c6dcea
DOI
10.1101/2020.05.27.120089
Open publication

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