Article
Activated K-RAS and its effect on morphological appearance.
Journal of biochemistry - 1 Sept 2014
Kiyokawa Etsuko, Minato Hiroshi
Abstract excerpt
RAS genes are frequently mutated in various human tumours. These mutations cause GTPase RAS to remain locked in constitutively active signals through the downstream cascades leading to proliferation. A series of earlier studies reported on the morphological appearance of cells upon RAS activation...
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