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Article

Clopidogrel dose adjustment after outpatient screening for CYP2C19 variant alleles: a pilot study.

Pharmacogenomics - 1 May 2014

Rossi Joseph S, Cammarata Michael, Dharmavaram Jayalalitha, Weck Karen, Walko Christine, Gabriel Don, Kuritzky Jack, Muldrew Kenneth, Stouffer George A

Abstract excerpt

This pilot study examined the feasibility of outpatient screening and clopidogrel dose adjustment for patients with previous percutaneous coronary intervention and at least one CYP2C19 loss-of-function allele. After screening a total of 211 outpatients, 50 patients were enrolled in a crossover study comparing 30 days of standard dose (75 mg) to 30 days of high-dose clopidogrel (150 mg). Platelet function was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C19

Share to Dose-Response Relationship, Drug

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Source

Identifiers

PMID: 24956245
DOI: 10.2217/pgs.14.17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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