Article
First analysis of the relation between CYP2C19 genotype and pharmacodynamics in patients treated with ticagrelor versus clopidogrel: the ONSET/OFFSET and RESPOND genotype studies.
Circulation. Cardiovascular genetics - 1 Dec 2010
Tantry Udaya S, Bliden Kevin P, Wei Cheryl, Storey Robert F, Armstrong Martin, Butler Kathleen, Gurbel Paul A
Abstract excerpt
BACKGROUND: The influence of cytochrome P450 (CYP) 2C19 genotype on platelet function in patients treated with ticagrelor versus clopidogrel is unknown. METHODS AND RESULTS: CYP2C19 (*1, *2, *3, *4, *5, *6, *7, *8, *17) genotyping was performed in patients with coronary artery disease treated wit...
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