Article
Platelet inhibition by adjunctive cilostazol versus high maintenance-dose clopidogrel in patients with acute myocardial infarction according to cytochrome P450 2C19 genotype.
JACC. Cardiovascular interventions - 1 Apr 2011
Kim In-Suk, Jeong Young-Hoon, Park Yongwhi, Park Ki-Soo, Yun Seong-Eun, Park Jeong-Rang, Hwang Seok-Jae, Koh Eun-Ha, Kwak Choong Hwan, Hwang Jin-Yong, Kim Sunjoo
Abstract excerpt
OBJECTIVES: The aim of this study was to assess the degree of platelet inhibition by adjunctive cilostazol in patients with acute myocardial infarction (AMI) according to hepatic cytochrome P450 2C19 (CYP2C19) genotype. BACKGROUND: Although adjunctive cilostazol intensifies platelet inhibition in AMI patients, it is not established whether this regimen can be free from the effect of CYP2C19 loss-of-function...
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