Article
Pharmacogenomics of anti-platelet therapy: how much evidence is enough for clinical implementation?
Journal of human genetics - 1 Jun 2013
Perry Christina G, Shuldiner Alan R
Abstract excerpt
Pharmacogenomics, the study of the genomics of drug response and adverse effects, holds great promise for more effective individualized (personalized) medicine. Recent evidence supports a role of loss-of-function (LOF) variants in the cytochrome P450 enzyme CYP2C19 as a determinant of clopidogrel...
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