Article
From Chickens to Humans: The Importance of Peptide Repertoires for MHC Class I Alleles.
Frontiers in immunology - 1 Jan 2020
Kaufman Jim
Abstract excerpt
In humans, killer immunoglobulin-like receptors (KIRs), expressed on natural killer (NK) and thymus-derived (T) cells, and their ligands, primarily the classical class I molecules of the major histocompatibility complex (MHC) expressed on nearly all cells, are both polymorphic. The variation of this receptor-ligand interaction, based on which alleles have been inherited, is known to play crucial roles in...
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