Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of adenosine receptor gene polymorphisms and in vivo adenosine A1 receptor binding in the human brain.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Dec 2014

Hohoff Christa, Garibotto Valentina, Elmenhorst David, Baffa Anna, Kroll Tina, Hoffmann Alana, Schwarte Kathrin, Zhang Weiqi, Arolt Volker, Deckert Jürgen, Bauer Andreas

Abstract excerpt

Adenosine A1 receptors (A1ARs) and the interacting adenosine A2A receptors are implicated in neurological and psychiatric disorders. Variants within the corresponding genes ADORA1 and ADORA2A were shown associated with pathophysiologic alterations, particularly increased anxiety. It is unknown so far, if these variants might modulate the A1AR distribution and availability in different brain regions. In this pilot...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Fluorodeoxyglucose F18

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Magnetic Resonance Imaging

Share to Positron-Emission Tomography

Share to Protein Binding

Share to Receptor, Adenosine A2A

Share to Xanthines

Source

Open in PubMed Open full text

Identifiers

PMID: 24943643
DOI: 10.1038/npp.2014.150
PMCID: PMC4229568

Genes

ADORA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of adenosine receptor gene polymorphisms and in vivo adenosine A1 receptor binding in the human brain.PMID 24943643Read ↗

A genetic variation in the adenosine A2A receptor gene contributes to variability in oscillatory alpha power in wake and sleep EEG and A1 adenosine receptor availability in the human brain.Semantic proximity Read ↗

Association between ADORA2A and DRD2 polymorphisms and caffeine-induced anxiety.Semantic proximity Read ↗

Adenosine A(2A) receptor gene: evidence for association of risk variants with panic disorder and anxious personality.Semantic proximity Read ↗

A genetic variation in the adenosine A2A receptor gene contributes to variability in oscillatory alpha power in wake and sleep EEG and A <sub>1</sub> adenosine receptor availability in the human brainSemantic proximity Read ↗

Effects of ADORA2A gene variation and caffeine on prepulse inhibition: a multi-level risk model of anxiety.Semantic proximity Read ↗

The RS685012 Polymorphism of ACCN2, the Human Ortholog of Murine Acid-Sensing Ion Channel (ASIC1) Gene, is Highly Represented in Patients with Panic Disorder.Semantic proximity Read ↗

Analysis of ADORA2A rs5760423 and CYP1A2 rs762551 Genetic Variants in Patients with Alzheimer's Disease.Semantic proximity Read ↗

Caffeine consumption and behavioral symptoms: influence of ADORA2A and DRD2 genes on inattention.Semantic proximity Read ↗

Neural Mechanism of a Sex-Specific Risk Variant for Posttraumatic Stress Disorder in the Type I Receptor of the Pituitary Adenylate Cyclase Activating Polypeptide.Semantic proximity Read ↗

PACAP receptor gene polymorphism impacts fear responses in the amygdala and hippocampus.Semantic proximity Read ↗

A genetic variation in the adenosine A2A receptor gene (ADORA2A) contributes to individual sensitivity to caffeine effects on sleep.Semantic proximity Read ↗

Association of the anxiogenic and alerting effects of caffeine with ADORA2A and ADORA1 polymorphisms and habitual level of caffeine consumption.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.