Article
Human Th2 but Not Th9 Cells Release IL-31 in a STAT6/NF-κB–Dependent Way
19 Jun 2014
Abstract excerpt
IL-31, a member of the IL-6 protein family, is one of the latest additions to the list of T cell-derived cytokines. Th2 cells are regarded as a main source of IL-31, which is produced in response to stimulation by IL-4. Because the development of Th9 cells also requires IL-4 as a polarizing cytokine, the current study investigates IL-31 production in human Th9 cells compared with Th2 cells. We found that,...
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