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Article

The potential role of IL-33/ST2 signaling in fibrotic diseases

16 Apr 2015

Abstract excerpt

IL-33, a new member of the IL-1F, is widely expressed throughout the body and can be up-regulated by stimulation with proinflammatory factors. It has been identified as a functional ligand for the plasma membrane receptor complex that is a heterodimer consisting of membrane-bound ST2L, which is a member of the IL-1R family, and IL-1RAcP. IL-33 is crucial for the induction of Th2 immune responses. Additionally,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25881899
DOI: 10.1189/jlb.3ru0115-012r

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