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Article

High resolution T association tests of complex diseases based on family data.

Annals of human genetics - 1 Mar 2005

Fan Ruzong, Knapp Michael, Wjst Matthias, Zhao Caixia, Xiong Momiao

Abstract excerpt

This paper proposes family based Hotelling's T(2) tests for high resolution linkage disequilibrium (LD) mapping or association studies of complex diseases. Assume that genotype data of multiple markers or haplotype blocks are available for a sample of nuclear families, in which some offspring are affected. Paired Hotelling's T(2) test statistics are proposed for a high resolution association study using parents...

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Identifiers

PMID: 15720300
DOI: 10.1046/j.1529-8817.2004.00151.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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