Article
Investigation of the involvement of MIR185 and its target genes in the development of schizophrenia.
Journal of psychiatry & neuroscience : JPN - 1 Nov 2014
Forstner Andreas J, Basmanav F B, Mattheisen Manuel, Böhmer Anne C, Hollegaard Mads V, Janson Esther, Strengman Eric, Priebe Lutz, Degenhardt Franziska, Hoffmann Per, Herms Stefan, Maier Wolfgang, Mössner Rainald, Rujescu Dan, Ophoff Roel A, Moebus Susanne, Mortensen Preben B, Børglum Anders D, Hougaard David M, Frank Josef, Witt Stephanie H, Rietschel Marcella, Zimmer Andreas, Nöthen Markus M, Miró Xavier, Cichon Sven
Abstract excerpt
BACKGROUND: Schizophrenia is a complex neuropsychiatric disorder of unclear etiology. The strongest known genetic risk factor is the 22q11.2 microdeletion. Research has yet to confirm which genes within the deletion region are implicated in schizophrenia. The minimal 1.5 megabase deletion contain...
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