Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The mechanism of sperm–egg interaction and the involvement of IZUMO1 in fusion

8 Nov 2010

Abstract excerpt

An average human ejaculate contains over 100 million sperm, but only a few succeed in accomplishing the journey to an egg by migration through the female reproductive tract. Among these few sperm, only one participates in fertilization. There might be an ingenious molecular mechanism to ensure that the very best sperm fertilize an egg. However, recent gene disruption experiments in mice have revealed that many...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21057513
DOI: 10.1038/aja.2010.70

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The mechanism of sperm–egg interaction and the involvement of IZUMO1 in fusionPMID 21057513Read ↗

Mechanisms of Fertilization—A View From the Study of Gene‐Manipulated MiceSemantic proximity Read ↗

Sperm-Egg InteractionSemantic proximity Read ↗

Sperm-Egg Fusion: A Molecular Enigma of Mammalian ReproductionSemantic proximity Read ↗

Novel insights into the molecular mechanism of sperm–egg fusion via IZUMO1Semantic proximity Read ↗

New insights into the molecular basis of mammalian sperm-egg membrane interactionsSemantic proximity Read ↗

Binding of sperm protein Izumo1 and its egg receptor Juno drives Cd9 accumulation in the intercellular contact area prior to fusion during mammalian fertilizationSemantic proximity Read ↗

Oocyte-triggered dimerization of sperm IZUMO1 promotes sperm–egg fusion in miceSemantic proximity Read ↗

TMEM95 is a sperm membrane protein essential for mammalian fertilizationSemantic proximity Read ↗

The molecular basis of sperm-oocyte membrane interactions during mammalian fertilizationSemantic proximity Read ↗

Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complexSemantic proximity Read ↗

An update of the regulatory factors of sperm migration from the uterus into the oviduct by genetically manipulated miceSemantic proximity Read ↗

Sperm–egg adhesion and fusion in mammalsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.