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Article

New insights into the molecular basis of mammalian sperm-egg membrane interactions

1 Nov 2007

Abstract excerpt

Fertilization is the process by which two terminally differentiated cells, the sperm and the egg, merge to form a totipotent cell, the zygote. This review addresses one of the culminating steps in getting sperm and egg together: the cell-cell interactions that allow the two gametes to fuse and create the zygote. Based on cell biological and genetic studies, major players include CD9 on the egg and Izumo on the...

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PMID: 17981561
DOI: 10.2741/2693

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