Article
Variant rs1906591 on chromosome 4q25 confers increased risk of cardioembolic stroke in Chinese patients.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Oct 2014
Luo Man, Li Jiaoxing, Lai Rong, Sun Xunsha, Wang Yufang, Xu Xiaowei, Sheng Wenli
Abstract excerpt
Ischemic stroke (IS) is a heterogeneous multifactorial disorder caused by both genetic and environmental factors. A genome-wide association study on stroke in Caucasians identified a variant on chromosome 4q25 that is significantly associated with IS, with the strongest risk for cardioembolic stroke (CES). The current study aims to investigate the association of the rs1906591 variant on 4q25 with IS through a...
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