Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke.

doi:10.1002/ana.21480

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Article

Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke.

Annals of neurology - 1 Oct 2008

Gretarsdottir Solveig, Thorleifsson Gudmar, Manolescu Andrei, Styrkarsdottir Unnur, Helgadottir Anna, Gschwendtner Andreas, Kostulas Konstantinos, Kuhlenbäumer Gregor, Bevan Steve, Jonsdottir Thorbjorg, Bjarnason Hjordis, Saemundsdottir Jona, Palsson Stefan, Arnar David O, Holm Hilma, Thorgeirsson Gudmundur, Valdimarsson Einar Mar, Sveinbjörnsdottir Sigurlaug, Gieger Christian, Berger Klaus, Wichmann H-Erich, Hillert Jan, Markus Hugh, Gulcher Jeffrey Robert, Ringelstein E Bernd, Kong Augustine, Dichgans Martin, Gudbjartsson Daniel Fannar, Thorsteinsdottir Unnur, Stefansson Kari

Abstract excerpt

OBJECTIVE: To find sequence variants that associate with the risk for ischemic stroke (IS), we performed a genome-wide association study. METHODS: We genotyped 1,661 Icelandic IS patients and 10,815 control subjects using the Infinium HumanHap300 chip (Illumina, San Diego, CA). A total of 310,881 single nucleotide polymorphisms (SNPs) were tested for association with IS, and the most significant signals were...

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PMID: 18991354
DOI: 10.1002/ana.21480

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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