Article
The association of the 4q25 susceptibility variant for atrial fibrillation with stroke is limited to stroke of cardioembolic etiology.
Stroke - 1 Sept 2010
Lemmens Robin, Buysschaert Ian, Geelen Veerle, Fernandez-Cadenas Israel, Montaner Joan, Schmidt Helena, Schmidt Reinhold, Attia John, Maguire Jane, Levi Christopher, Jood Katarina, Blomstrand Christian, Jern Christina, Wnuk Marcin, Slowik Agniezska, Lambrechts Diether, Thijs Vincent
Abstract excerpt
BACKGROUND AND PURPOSE: Genome-wide association studies recently identified 2 variants on chromosome 4q25 as susceptibility factors for atrial fibrillation. Interestingly, these variants were subsequently also shown to be associated with stroke. However, it remains unclear whether 4q25 associates with all the stroke subtypes or with cardioembolic stroke in particular, which is often attributable to atrial...
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