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Single-Nucleotide Polymorphism rs17611 of Complement Component 5 Shows Association with Ischemic Stroke in Northeast Chinese Population.

Genetic testing and molecular biomarkers - 1 Dec 2016

Guo Liang, Zheng Liqiang, Guo Xiaofan, Chang Ye, Zhou Xinghu, Sun Yingxian

Abstract excerpt

BACKGROUND: Complement component 5 (C5) has been described to play an important role in the development and progression of atherosclerosis and cardiovascular disease. Our aim was to determine whether genetic variation of C5 was associated with ischemic stroke (IS) in northeast Chinese population. METHODS: We used a case-control study involving 386 IS patients and 386 non-IS controls from a rural population and...

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PMID: 27768391
DOI: 10.1089/gtmb.2016.0125

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