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Article

NQO1 polymorphism and susceptibility to ischemic stroke in a Chinese population.

BMC medical genomics - 22 Aug 2024

Wang Min, Shen Ying, Gao Yuan, Chen Huaqiu, Duan Fuhui, Li Siying, Wang Guangming

Abstract excerpt

BACKGROUND: Ischemic stroke (IS) is a major cause of death and disability worldwide. Genetic factors are important risk factors for the development of IS. The quinone oxidoreductase 1 gene (NQO1) has antioxidant, anti-inflammatory, and cytoprotective properties. Thus, in this study, we investigated the relationship between NQO1 gene polymorphism and the risk of IS. METHODS: Peripheral blood was collected from 143...

Topics

Aged
Female
Humans
Male
Middle Aged
Case-Control Studies
China
East Asian People
Genetic Predisposition to Disease
Ischemic Stroke
NAD(P)H Dehydrogenase (Quinone)

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 39174970
DOI: 10.1186/s12920-024-01992-7
PMCID: PMC11342592

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-39174970-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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