Article

<i>Streptococcus pneumoniae</i> evades host cell phagocytosis and limits host mortality through its cell wall anchoring protein PfbA

2019-04-05

Abstract excerpt

Streptococcus pneumoniae is a Gram-positive bacterium belonging to the oral streptococcus species, mitis group. This pathogen is a leading cause of community-acquired pneumonia, which often evades host immunity and causes systemic diseases, such as sepsis and meningitis. Previously, we reported that PfbA is a β-helical cell surface protein contributing to pneumococcal adhesion to and invasion of human epithelial c...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1aa3b58d-2ab2-5449-ad99-50150d07a283
DOI: 10.1101/599001

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

<i>Streptococcus pneumoniae</i> evades host cell phagocytosis and limits host mortality through its cell wall anchoring protein PfbADOI 10.1101/599001Read

Streptococcus pneumoniae Evades Host Cell Phagocytosis and Limits Host Mortality Through Its Cell Wall Anchoring Protein PfbASemantic proximity Read

Molecular pathogenesis of pneumococcal pneumoniaSemantic proximity Read

Recent advances in understanding the molecular basis of group B<i>Streptococcus</i>virulenceSemantic proximity Read

PfbA, a novel plasmin- and fibronectin-binding protein of Streptococcus pneumoniae, contributes to fibronectin-dependent adhesion and antiphagocytosis.Semantic proximity Read

Pathogenesis of pneumococcal infectionSemantic proximity Read

Structural and Functional Analysis of Cell Wall-anchored Polypeptide Adhesin BspA in Streptococcus agalactiaeSemantic proximity Read

The choline-binding proteins PspA, PspC and LytA of <i>Streptococcus pneumoniae</i> and their role on host cellular adhesion and damageSemantic proximity Read

Bps polysaccharide of <i>Bordetella pertussis</i> resists antimicrobial peptides by functioning as a dual surface shield and decoy and converts <i>Escherichia coli</i> into a respiratory pathogenSemantic proximity Read

PcpA Promotes Higher Levels of Infection and Modulates Recruitment of Myeloid-Derived Suppressor Cells during Pneumococcal Pneumonia.Semantic proximity Read

A genetic interaction screen in <i>Streptococcus pneumoniae</i> identifies functionally redundant vaccine candidate proteins CbpC and CbpJSemantic proximity Read

The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitisSemantic proximity Read

<i>Streptococcus pyogenes</i> adhesion and colonizationSemantic proximity Read