Article
Critical protective role for MCP-1 in pneumonic Burkholderia mallei infection.
Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 2010
Goodyear Andrew, Jones Abby, Troyer Ryan, Bielefeldt-Ohmann Helle, Dow Steven
Abstract excerpt
Burkholderia mallei is a gram-negative bacterial pathogen of domestic equidae and humans that can cause severe, rapidly life-threatening pneumonic infections. Little is known regarding the role of chemokines and early cellular immune responses in protective immunity to pulmonary infection with B. mallei. Although the role of MCP-1 in gram-positive bacterial infections has been previously investigated, the role of...
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