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Article

Cancer stem cell phenotype is supported by secretory phospholipase A2 in human lung cancer cells.

The Annals of thoracic surgery - 1 Aug 2014

Bennett Daine T, Deng Xin-Sheng, Yu Jessica A, Bell Marshall T, Mauchley David C, Meng Xianzhong, Reece T Brett, Fullerton David A, Weyant Michael J

Abstract excerpt

BACKGROUND: Lung cancer stem cells (CSCs) are a subpopulation of cells that drive growth, invasiveness, and resistance to therapy. Inflammatory eicosanoids are critical to maintain this malignant subpopulation. Secretory phospholipase A2 group IIa (sPLA2) is an important mediator of the growth an...

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Identifiers

PMID: 24928671
DOI: 10.1016/j.athoracsur.2014.04.044
PMCID: PMC4764123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24928671-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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