Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stearoyl-CoA desaturase-1 is a key factor for lung cancer-initiating cells

5 Dec 2013

Abstract excerpt

In recent years, studies of cancer development and recurrence have been influenced by the cancer stem cells (CSCs)/cancer-initiating cells (CICs) hypothesis. According to this, cancer is sustained by highly positioned, chemoresistant cells with extensive capacity of self renewal, which are responsible for disease relapse after chemotherapy. Growth of cancer cells as three-dimensional non-adherent spheroids is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer, Hypoxia, and Metabolism
Share to Cancer, Lipids, and Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24309934
DOI: 10.1038/cddis.2013.444

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stearoyl-CoA desaturase-1 is a key factor for lung cancer-initiating cellsPMID 24309934Read ↗

Sphere-forming culture enriches liver cancer stem cells and reveals Stearoyl-CoA desaturase 1 as a potential therapeutic targetSemantic proximity Read ↗

Inhibition of Stearoyl-CoA Desaturase 1 expression in human lung adenocarcinoma cells impairs tumorigenesis.Semantic proximity Read ↗

Targeting the SREBP-1/Hsa-Mir-497/SCAP/FASN Oncometabolic Axis Inhibits the Cancer Stem-like and Chemoresistant Phenotype of Non-Small Cell Lung Carcinoma Cells.Semantic proximity Read ↗

CytoMatrix for a reliable and simple characterization of lung cancer stem cells from malignant pleural effusionsSemantic proximity Read ↗

Suppression of a cancer stem-like phenotype mediated by alpha-lipoic acid in human lung cancer cells through down-regulation of β-catenin and Oct-4.Semantic proximity Read ↗

Targeting a Lipid Desaturation Enzyme, SCD1, Selectively Eliminates Colon Cancer Stem Cells through the Suppression of Wnt and NOTCH SignalingSemantic proximity Read ↗

Stearoyl coenzyme A desaturase-1: multitasker in cancer, metabolism, and ferroptosisSemantic proximity Read ↗

Identification of a set of genes potentially responsible for resistance to ferroptosis in lung adenocarcinoma cancer stem cellsSemantic proximity Read ↗

Aldehyde dehydrogenase-1 is a specific marker for stem cells in human lung adenocarcinoma.Semantic proximity Read ↗

Identification of a set of genes potentially responsible for resistance to ferroptosis in lung adenocarcinoma cancer stem cellsSemantic proximity Read ↗

Profiling of Aldehyde Dehydrogenase Isoforms in In Vitro Formed Tumorspheres.Semantic proximity Read ↗

Stemness and inducing differentiation of small cell lung cancer NCI-H446 cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.