Article
Profiling of Aldehyde Dehydrogenase Isoforms in In Vitro Formed Tumorspheres.
Anticancer research - 1 Nov 2021
Tsochantaridis Ilias, Voulgaridou Georgia-Persephoni, Giatromanolaki Alexandra, Koukourakis Michael I, Panayiotidis Mihalis I, Pappa Aglaia
Abstract excerpt
BACKGROUND/AIM: Aldehyde dehydrogenases (ALDHs) are considered as markers for normal and cancer stem cells (CSC) and are involved in cell metabolism, proliferation, differentiation, stemness, and retinoic acid (RA) biosynthesis. The aim of the present study was to identify the ALDH isoforms that are associated with the CSC phenotype in non-small cell lung and hepatocellular carcinomas. MATERIALS AND METHODS: We...
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