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Article

Aldehyde dehydrogenase-1 is a specific marker for stem cells in human lung adenocarcinoma.

Medical oncology (Northwood, London, England) - 1 Jun 2012

Liang Dong, Shi Yuzhi

Abstract excerpt

To investigate whether aldehyde dehydrogenase-1 (ALDH-1) in human lung cancer can be used as a sorting marker for stem cells in targeted therapies against human lung cancer. Spheres were induced by incubating cancer cells in a serum-free medium and formed with epidermal growth factor and fibroblast growth factor-10 (FGF10). Spheroid cells were combined with flow cytometry using the Aldefluor reagent to separate...

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Identifiers

PMID: 21484084
DOI: 10.1007/s12032-011-9933-9

Genes

ABCG2
FGF10

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