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Article

Analysis of tumor-host interactions by gene expression profiling of lung adenocarcinoma xenografts identifies genes involved in tumor formation.

Molecular cancer research : MCR - 1 Mar 2005

Creighton Chad J, Bromberg-White Jennifer L, Misek David E, Monsma David J, Brichory Frank, Kuick Rork, Giordano Thomas J, Gao Weimin, Omenn Gilbert S, Webb Craig P, Hanash Samir M

Abstract excerpt

Tumor cell lines are relied on extensively for cancer investigations, yet cultured cells in an in vitro environment differ considerably in behavior compared with those of the same cancer cells that proliferate and form tumors in vivo. To uncover gene expression changes related to tumor formation, gene expression profiles of human lung adenocarcinoma (A549) cells grown as lung tumors in immune-compromised mice...

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PMID: 15798092
DOI: 10.1158/1541-7786.MCR-04-0189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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