Article
Sphingomyelinase-like phosphodiesterase 3b expression levels determine podocyte injury phenotypes in glomerular disease.
Journal of the American Society of Nephrology : JASN - 1 Jan 2015
Yoo Tae-Hyun, Pedigo Christopher E, Guzman Johanna, Correa-Medina Mayrin, Wei Changli, Villarreal Rodrigo, Mitrofanova Alla, Leclercq Farah, Faul Christian, Li Jing, Kretzler Matthias, Nelson Robert G, Lehto Markku, Forsblom Carol, Groop Per-Henrik, Reiser Jochen, Burke George William, Fornoni Alessia, Merscher Sandra
Abstract excerpt
Diabetic kidney disease (DKD) is the most common cause of ESRD in the United States. Podocyte injury is an important feature of DKD that is likely to be caused by circulating factors other than glucose. Soluble urokinase plasminogen activator receptor (suPAR) is a circulating factor found to be e...
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