Article
Draft genome sequences of two super-extensively drug-resistant isolates of Mycobacterium tuberculosis from China.
FEMS microbiology letters - 1 Oct 2013
Lin Nan, Liu Zhangyi, Zhou Jie, Wang Shihua, Fleming Joy
Abstract excerpt
The prevalence of drug-resistance in Mycobacterium tuberculosis is already having a negative impact on the control of tuberculosis. We report the draft genome sequences of two super-extensively drug-resistant M. tuberculosis isolates from China, FJ05194 (lineage 2) and GuangZ0019 (lineage 4), and compare them with the H37Rv reference strain to identify possible sources of genetic variation associated with their...
Topics
- China
- DNA, Bacterial
- Extensively Drug-Resistant Tuberculosis
- Genetic Variation
- Genome, Bacterial
- Molecular Sequence Data
- Mutation
- Mycobacterium tuberculosis
- Polymorphism, Single Nucleotide
