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Article

Pulmonary adenocarcinoma mutation profile in smokers with smoking-related interstitial fibrosis.

International journal of chronic obstructive pulmonary disease - 1 Jan 2014

Primiani Andrea, Dias-Santagata Dora, Iafrate A John, Kradin Richard L

Abstract excerpt

Cigarette smoking is an established cause of lung cancer. However, pulmonary fibrosis is also an independent risk factor for the development of lung cancer. Smoking-related interstitial fibrosis (SRIF) has recently been reported. We hypothesized that adenocarcinomas in lungs with SRIF might show distinct molecular changes and examined the molecular phenotype of 168 resected lung adenocarcinomas in lungs with and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to In Situ Hybridization, Fluorescence

Share to Lung Diseases, Interstitial

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Source

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Identifiers

PMID: 24920890
DOI: 10.2147/COPD.S61932
PMCID: PMC4043428

Genes

ALK
EGFR
KRAS
MET
ROS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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