Article
Association between the lengths of GT dinucleotide repeat in the PIK3CA gene with breast cancer risk.
Medical oncology (Northwood, London, England) - 1 Jul 2014
Heshmatpour Najmeh, Hematti Simin, Hejazi Seyyed Hossein, Safari Forousan, Tavassoli Manoochehr
Abstract excerpt
The phosphatidylinositol 3-kinase (PI3 K)/Akt signaling pathway is one of the most commonly mutated pathways in breast cancer. To date, there has been no study on polymorphism of phosphatidylinositol-3,4-bisphosphonate 3-kinase, catalytic subunit alpha (PIK3CA) gene microsatellites and their link with breast cancer risk. In the present study, we investigate the guanine-thymine (GT) dinucleotide repeat...
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