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Article

Glucokinase diabetes in 103 families from a country-based study in the Czech Republic: geographically restricted distribution of two prevalent GCK mutations.

Pediatric diabetes - 1 Dec 2010

Pruhova Stepanka, Dusatkova Petra, Sumnik Zdenek, Kolouskova Stanislava, Pedersen Oluf, Hansen Torben, Cinek Ondrej, Lebl Jan

Abstract excerpt

BACKGROUND: Glucokinase diabetes, also called GCK-MODY or maturity-onset diabetes of the young type 2 (MODY2), is caused by heterozygous mutations in the gene encoding glucokinase (GCK). OBJECTIVE: The aim of study was to investigate the current prevalence of GCK mutations in a large cohort of Czech patients with typical clinical appearance of GCK-MODY. In addition, we reanalyzed the negative results obtained...

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Source

Identifiers

PMID: 20337973
DOI: 10.1111/j.1399-5448.2010.00646.x

Genes

GCK

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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