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Article

GCK gene mutations are a common cause of childhood-onset MODY (maturity-onset diabetes of the young) in Turkey.

Clinical endocrinology - 1 Sept 2016

Haliloglu Belma, Hysenaj Gerald, Atay Zeynep, Guran Tulay, Abalı Saygın, Turan Serap, Bereket Abdullah, Ellard Sian

Abstract excerpt

OBJECTIVE: Inactivating heterozygous mutations in the GCK gene are a common cause of MODY and result in mild fasting hyperglycaemia, which does not require treatment. We aimed to identify the frequency, clinical and molecular features of GCK mutations in a Turkish paediatric cohort. DESIGN AND PATIENTS: Fifty-four unrelated probands were selected based on the following criteria: age of diagnosis ≤17 years, family...

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Source

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Identifiers

PMID: 27256595
DOI: 10.1111/cen.13121
PMCID: PMC4988380

Genes

GCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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