Article
Angiopoietin-1 is regulated by miR-204 and contributes to corneal neovascularization in KLEIP-deficient mice.
Investigative ophthalmology & visual science - 10 Jun 2014
Kather Jakob N, Friedrich Julian, Woik Nicole, Sticht Carsten, Gretz Norbert, Hammes Hans-Peter, Kroll Jens
Abstract excerpt
PURPOSE: Corneal neovascularization can cause loss of vision. The introduction of anti-VEGF therapy has been a major improvement in therapeutic options. Recently, we established Kelch-like Ect2-interacting protein (KLEIP/KLHL20) knockout mice as a model of spontaneous corneal neovascular dystrophy. The aim of the present study was to characterize corneal neovascularization in progressive corneal dystrophy in...
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