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Article

Dynamics of pfcrt alleles CVMNK and CVIET in chloroquine-treated Sudanese patients infected with Plasmodium falciparum.

Malaria journal - 12 Mar 2010

Gadalla Nahla B, Elzaki Salah Eldin, Mukhtar Ebtihal, Warhurst David C, El-Sayed Badria, Sutherland Colin J

Abstract excerpt

BACKGROUND: Parasite resistance to the anti-malarial drug chloroquine is common in eastern Sudan. Dynamic within-host changes in the relative abundance of both sensitive and resistant Plasmodium falciparum parasites were examined in a cohort of chloroquine-treated patients presenting with uncomplicated falciparum malaria, using a novel allele-specific quantitative approach. METHODS: Treatment outcomes were...

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Identifiers

PMID: 20226032
DOI: 10.1186/1475-2875-9-74
PMCID: PMC2848148

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Source receipt: pubmed, retrieved 7 Sept 2026.

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